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The fetal origins hypothesis
A suboptimal maternal environment during pregnancy programs the functioning of fetal tissues and modifies the risk of disease in adult life. Just consider:
- Physical characteristics like mom’s poor nutrition and/or low birth weight, a marker of adverse intrauterine milieu and health is associated with increased risk of coronary heart disease, hypertension, type 2 diabetes, and osteoporosis in the child later on.
- Slow prenatal and infant growth is linked with hostility in adult life .
- Conversely, low birth weight of the baby increases all-cause mortality and cardiovascular mortality in both mothers and fathers.
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