Tag Archive | epigenetic

Intergenerational effects are involved in chronic diseases like autism

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The fetal origins hypothesis

A suboptimal maternal environment during pregnancy programs the functioning of fetal tissues and modifies the risk of disease in adult life. Just consider:

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Leaky gut syndrome and autism Gut Digestion are key to rising chronic disorders  
Causes of alcohol hangover Paleolithic or stone-age diet overview
GERD and asthma  GERD or chronic heartburn and acupuncture 
Effect of gut bacteria starts during pregnancy Does honey benefit cough?
Breast milk benefits and alternatives FOMAP diet: implications in health and sickness
Cranberry juice versus antibiotics for urinary tract infections ADHD: Causes, role of diet, gut and treatment
Migraine: triggers and natural treatments Food allergies and intolerances
Does Vegetarian diet reduce mortality? Nutritional supplements for liver disease
Does St Johns Wort help in Hot Flashes and menopause? Autism-Gut Axis: Role of maternal-fetal immune function
Do probiotics improve gut function and strengthen intestinal barrier? Health benefits of probiotics and prebiotics 
Is kava bad for liver Fish type, mercury toxicity & health v benefits: Farmed fish versus wild
Is fasting good or bad for health  Food triggers for migraine and helpful natural supplements
Is VitaminD deficiency a growing epidemic. maybe?  Mangosteen is not the same as mango 

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Autism: Celecoxib COX-2 nonsteroidal antiinflammatory agent improves symptoms

COX-2 inhibitor celecoxib

  1. COX-2 inhibitor effective against inflammatory conditions like arthritis
  2. COX-2 inhibitors rebalance type-1 and type-2 immune dysfunction
  3. COX-2 inhibitors prevent death of brain cells
  4. Beneficial effects of celecoxib  in early schizophrenia (Muller 2011)
  5. Beneficial effect of celecoxib as adjunct to risperidone in schizophrenia (Akhondzadeh 2007)
  6. Beneficial effect Aspirin as adjuvant to usual antipsychotic treatment of schizophrenia (Laan et al 2010)
  7. Beneficial effects in major depression

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 Guide to Alternative Medicine and the Digestive System

Zinc Deficiency and Autism: Is there a link?

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How can zinc affect a disorder with potentially genetic basis

Environmental influences like trace metal deficiency or toxic metal levels may alter gene expression and is believed to be central to pathogenesis of many disorders (epigenetic) with underlying genetic basis.

The study detailed below in the article iss consistent with the role of gut in general and more specifically alterations in digestion/nutritional factors in pathogenesis of autism spectrum disorders.

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