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Anti-gliadin antibodies in autism

Gluten free diet is becoming increasingly popular across the Western society and even more so among those suffering from autism. ..Study by Dr. Lau and colleagues  from the Celiac Disease Center in Columbia University, New York, lends further support to the use of gluten free diet by autistic subjects.

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Learn about 12-point autism treatment program   

Does proximity to freeway traffic  increase risk of autism

 

All fish are not same: Low v high mercury fish   
Quinoa: one complete high protein food  Health benefits of probiotics and prebiotics
Antibiotics in meat: A case for organic food

 

FODMAP diet: one type of elimination diet to try
Zinc supplements boost immune sytem and reduce respiratory infections

 

Turmeric: A must-have healthy spice in kitchen.
Use of elimination diet in autism Food allergies and intolerance are not the same

 

Do cranberry and/or mannose protect against  urinary tract infections or UTI   Coconut oil repairs unhealthy skin

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Blog: Digestion, Health and Nutrition

Intergenerational effects are involved in chronic diseases like autism

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The fetal origins hypothesis

A suboptimal maternal environment during pregnancy programs the functioning of fetal tissues and modifies the risk of disease in adult life. Just consider:

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Leaky gut syndrome and autism Gut Digestion are key to rising chronic disorders  
Causes of alcohol hangover Paleolithic or stone-age diet overview
GERD and asthma  GERD or chronic heartburn and acupuncture 
Effect of gut bacteria starts during pregnancy Does honey benefit cough?
Breast milk benefits and alternatives FOMAP diet: implications in health and sickness
Cranberry juice versus antibiotics for urinary tract infections ADHD: Causes, role of diet, gut and treatment
Migraine: triggers and natural treatments Food allergies and intolerances
Does Vegetarian diet reduce mortality? Nutritional supplements for liver disease
Does St Johns Wort help in Hot Flashes and menopause? Autism-Gut Axis: Role of maternal-fetal immune function
Do probiotics improve gut function and strengthen intestinal barrier? Health benefits of probiotics and prebiotics 
Is kava bad for liver Fish type, mercury toxicity & health v benefits: Farmed fish versus wild
Is fasting good or bad for health  Food triggers for migraine and helpful natural supplements
Is VitaminD deficiency a growing epidemic. maybe?  Mangosteen is not the same as mango 

Digestion, Health, Nutrition                                   Facebook Dr. Anil

Altered Fermentation of Undigested Food by Gut Bacteria in Autism: Clues to Treatment Strategies

Evidence indicates that gut bacteria may be at the crossroads of genetics, digestive enzymes of  autism spectrum disorders.  This study of altered corroborates the hypothesis and provides clues to how altered bacteria may be involved in causing and sustaining autism.

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Learn about 12-point autism treatment program          OR more topics of interest below

Chronic low back pain: Tried acupuncture?

Chronic acid reflux and acupuncture?

Vegetarian diet: Does it affect mortality?

 Natural treatments of depression

Got Migraine? Food triggers and natural treatments!

FODMAP diet: one type of elimination diet to try

Gut bacteria in fetus and future health? 

Constipation: How to take care of business 

Intestinal gas: Do you have it? 

Vitamin D deficiency is common: You may have it!

Do cranberry and/or mannose protect against urinary tract infections or UTI

Leaky gut syndrome

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Blog: Digestion, Health and Nutrition

Does Influenza and Antibiotic Use During Pregnancy Increase Autism

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  • Infection results not only just immune activation but also increased intestinal permeability or leaky gut along with alterations of intestinal bacteria or dysbiosis. Such intestinal changes can results in passage of potentially noxious substances/signals across the placenta to the developing fetus.
  • These chemicals transferred to fetus and its developing brain may include maternal antibodies as a result of infection, abnormal neurochemical signals due to altered brain-gut-bacteria communications in mother, absorbed bacterial toxic products with their antibodies as well as potentially noxious semi-digested food products.

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Effect of Gut Bacteria on Ultimate Health Starts During Pregnancy

Microbial transfer and contact of the mother with the growing baby in uterus as well as during delivery and breastfeeding cannot be ignored. In fact early exposures have affect the long term bacterial finger-print of the individual also termed as microbiological programming.

ADHD: Causes, role of diet, gut and treatment Role of good teeth and gums in autism
N-acetyl cysteine for irritability in autism Lifestyle measures to improve upper digestive health 
Publication bias SSRIs antidepressants for repetitive behavior in autism Rising autism and Mystery of male preponderance
Autism and mitochondrial dysfunction http://wp.me/p1WoF9-cY Food colors, additives elimination diet and ADHD
Coexisting autism and ADHD: Role of shared heredity Fish Mercury toxicity versus health benefits
 Homeopathy: Fact or fiction Probiotics/prebioticsand their health benefits
 Hiccups: Natural treatments FODMAP diet and health implications 
Zinc supplements and reducing risk of  respiratory infections Turmeric: A must have healthy spice in kitchen  
 Fasting: Health benefits and longevity  Food allergies and intolerances  
Cranberry, mannose for preventing urinary tract infections or  UTI Risks of GERD heartburn PPI drugs keep piling up     
Micronutrients in  autism superior to medications  Autism controversy: Do patients have more constipation  
Leaky gut syndrome  Mangosteen: Is it good for health?
Autism: Role of leaky gut Autism: Role of gut bacteria
Intestinal bacteria in health and disease   L-carnitine is of benefit in autism
Vitamin D and autism Autism controversy: Role of Vitamin D
Migraine triggers and natural treatments  Celiac disease or gluten sensitive enteropathy

 

Is Autism an Immune Disorder?

Presented By Anil Minocha MD, author: Guide to Alternative Medicine and the Digestive System

This link is a response to an article in NY Times on this issue, really worth a read, no matter what you believe is at the root of this disorder:

http://roosclues.blogspot.com/2012/08/critique-of-ny-times-article-immune.html

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Autism and ADHD: Role of abnormal mitochondrial function

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Enteric nervous system or second brain is more susceptible to mitochondrial dysfunction than brain

  • Nervous system of the gut also known as enteric nervous system is susceptible to mitochondrial dysfunction even more than the brain and is consistent with increased prevalence of gastrointestinal symptoms in patients with primary inherited mitochondrial disorders.
  • Not all regions of the gut and enteric nervous system or the “Second Brain” are equally affected during illness, a phenomenon seen in the central nervous system as well.

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Co-existing Autism and ADHD: shared hereditary factors?

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Maternal, Natal Risk Factors for Autism

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Dr. Gardener and colleagues from the Department of Epidemiology, Harvard School of Public Health, Boston, MA conducted a metaanalysis of the studies on the effect of perinatal and neonatal risk factors that contribute to risk for autism. These investigators published their findings in the journal Pediatrics 2011.

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 Guide to Alternative Medicine and the Digestive System

 

Why is there a gender gap in autism

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Rising tide of autism with widening gender gap is not just in the West

According to Lai and colleagues from the Department of Physical Medicine and Rehabilitation, Chia-Yi Christian Hospital, Taiwan, an analysis of registry data from 2004 to 2010 revealed that between 2004 to 2010, the registered cases between 3 and 17 years old increased from 3995 to 8072 annually. Even more importantly, the prevalence gender rate ratio ranged from 5.64:1 to 6.06:1. Autism was seen more in urban than rural areas.

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 Guide to Alternative Medicine and the Digestive System

               Join Facebook group Autism: It’s Gut Stupid

Learn about 12-point autism treatment program   OR more topics of interest below

Tricyclic antidepressants and autism

All fish are not same: Low v high mercury fish  

Quinoa: one complete high protein food

Health benefits of probiotics and prebiotics

Oral health in autism: dental caries and gums gingivitis

FODMAP diet: one type of elimination diet to try

Zinc supplements boost immune sytem and reduce respiratory infections

Turmeric: A must-have healthy spice in kitchen.

Use of elimination diet in autism

Food allergies and intolerance are not the same

Do cranberry and/or mannose protect against  urinary tract infections or UTI 

Coconut oil repairs unhealthy skin

Facebook AutismItsGutStupid group page       Facebook Dr. Anil      Blog: Digestion, Health and Nutrition

Micronutrients in  autism superior to medications

Autism controversy: Do patients have more constipation 

Leaky gut syndrome 

Mangosteen: Is it good for health? 

Autism: Role of leaky gut

Autism: Role of gut bacteria  

Intestinal bacteria in health and disease  

L-carnitine is of benefit in autism

Autism L-carnitine goo.gl/0wZSz

Autism controversy: Role of Vitamin D

Migraine triggers and natural treatments 

Celiac disease or gluten sensitive enteropathy

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Dental Health and Sickness in Autism

Join Facebook group Autism: It’s Gut Stupid

Bad teeth and gum equal to inflammation. The pro-inflammation cytokines, chemical signals are thus circulating throughout and effecting the whole body including the heart and the brain.

Inflammation is an important component of chronic disease states including disorders affecting brain. Neuro-inflammation creates disruption in brain cells as well as signalling pathways and as such may have important role in neuro-behavioral manifestations of autism spectrum disorders. Maintaining good oral-dental health is part of the 12-point autism treatment program.

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More topics of interest

 Join Facebook group Autism: It’s Gut Stupid

Learn about 12-point autism treatment program  

Tricyclic antidepressants and autism

All fish are not same: Low v high mercury fish  

Quinoa: one complete high protein food

Health benefits of probiotics and prebiotics

Oral health in autism: dental caries and gums gingivitis

FODMAP diet: one type of elimination diet to try

Zinc supplements boost immune sytem and reduce respiratory infections

Turmeric: A must-have healthy spice in kitchen.

Use of elimination diet in autism

Food allergies and intolerance are not the same

Do cranberry and/or mannose protect against  urinary tract infections or UTI 

Coconut oil repairs unhealthy skin

 

Zinc Deficiency and Autism: Is there a link?

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How can zinc affect a disorder with potentially genetic basis

Environmental influences like trace metal deficiency or toxic metal levels may alter gene expression and is believed to be central to pathogenesis of many disorders (epigenetic) with underlying genetic basis.

The study detailed below in the article iss consistent with the role of gut in general and more specifically alterations in digestion/nutritional factors in pathogenesis of autism spectrum disorders.

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High Homocysteine, Low Vitamin Levels in Autism in Different Societies: Implicate Vitamins B12, Folic Acid, B6 in causative factors

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Multiple Western studies have demonstrated high levels of homocysteine in autism spectrum disorders. While autism is more common in th West, a similar correlation in Eastern societies also would lend support to hypothesis that folate-B12-homocyteine metabolism reactions may play a key role in environmental factors in autism.

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Blog: Digestion, Health and Nutrition

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Brain Disorders and Gut Bacteria Connection: Multiple Sclerosis Example

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Potential therapeutic strategies to treat multiple sclerosis and other neurological diseases like autism if Gut Bugs and Brain theory is confirmed

  • Repopulation of gut bacteria
  • Immunization against bacterial antigens
  • Antibiotics targeted against specific pathogens
  • Probiotics to alter gut bacteraia balance to modify immune system

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More topics of interest

More topics of interest below or go and Join Facebook group: AutismItsGutStupid

Leaky gut syndrome and autism Gut Digestion are key to rising chronic disorders  
Causes of alcohol hangover Paleolithic or stone-age diet overview
GERD and asthma  GERD or chronic heartburn and acupuncture 
Effect of gut bacteria starts during pregnancy Does honey benefit cough?
Breast milk benefits and alternatives FOMAP diet: implications in health and sickness
Cranberry juice versus antibiotics for urinary tract infections ADHD: Causes, role of diet, gut and treatment
Migraine: triggers and natural treatments Food allergies and intolerances
Does Vegetarian diet reduce mortality? Nutritional supplements for liver disease
Does St Johns Wort help in Hot Flashes and menopause? Autism-Gut Axis: Role of maternal-fetal immune function
Do probiotics improve gut function and strengthen intestinal barrier? Health benefits of probiotics and prebiotics 
Is kava bad for liver Fish type, mercury toxicity & health v benefits: Farmed fish versus wild
Is fasting good or bad for health  Food triggers for migraine and helpful natural supplements
Is VitaminD deficiency a growing epidemic. maybe?  Mangosteen is not the same as mango 

Digestion, Health, Nutrition                                   Facebook Dr. Anil

Other topics of interest:

  1. Autism, leaky gut and elimination diets
  2. Can probiotics strengthen selective intestinal barrier or leaky gut?
  3. Melatonin is not just for sleep. It helps gut too
  4. Toileting posture: Taking care of business well!

Facebook AutismItsGutStupid group page       Facebook Dr. Anil    Blog: Digestion, Health and Nutrition

This acid from food links autism with gut bacteria

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  • Propionic acid is contained in many food preservatives. Calcium propionate is FDA approved food preservative widely used in wheat, bread, cheese, juices, as well as dried fruit.
  • Propionic acid in food represents only a small fraction of what is encountered in gut as a result of bacterial metabolism.
  • Absorbed prioinic acid once absorbed into the blood circulation crosses the blood brain barrier and enters the brain where it can exert its affects.

Propionic acid or propionate in healthy kids

  • Consumption of large amounts of propionate makes kids irritable, inattentive,  and restless associated with sleep problems [Dengate 2002]

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12 point autism treatment program or more topics of interest below

Doctor, I have Intestinal Gas  Cranberry juice versus antibiotics for urinary tract infections
Effect of gut bacteria starts during pregnancy Buckwheat: complete gluten free alternative with benefits against many diseases
Fructose as artificial sweetener Probiotics help irritable bowel syndrome
Heartburn, GERD and acid reflux Heartburn, GERD and acid reflux
Food colors, elimination diet and ADHD Organic foods versus conventional foods
Brain dysfunction? learn about glial cells  Intestinal bacteria: Health or sickness?
Treat chronic inflammation naturally  Leaky gut syndrome: Do you have it?
Roots of Future Health Are Sown By Gut Bacteria During Fetal Life Ketogenic diet for brain disorders
Paleolithic diet: what is it and how is it different? Stress and gut: Your gut feelings!

    Join Facebook group Autism: It’s Gut Stupid

Is Vitamin D deficiency involved in autism?

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Vitamin D deficiency has been implicated in pathogenesis of multiple diverse diseases including neuro-psychiatric disorders like schizophrenia.

  • Evidence supports a role of suboptimal vitamin D levels in depression.
  • Autism shares many of the in-utero risk factors with schizophrenia.

Click to read full article

Learn about 12-point autism treatment program   OR more topics of interest below

Omega 3 fatty acids and risk of autism

All fish are not same: Low v high mercury fish  

Quinoa: one complete high protein food

Health benefits of probiotics and prebiotics

Oral health in autism: dental caries and gums gingivitis

FODMAP diet: one type of elimination diet to try

Zinc supplements boost immune sytem and reduce respiratory infections

Turmeric: A must-have healthy spice in kitchen.

Use of elimination diet in autism

Food allergies and intolerance are not the same

Do cranberry and/or mannose protect against  urinary tract infections or UTI 

Coconut oil repairs unhealthy skin


Autism prevalence and gut-brain connection: Treating based on what we know

      Join Facebook group Autism: It’s Gut Stupid    Facebook Dr. Anil

Is the brain dysfunction of autism primary or secondary

What causes autism? Is the problem mainly in brain or the brain effects are secondary? Alterations in pace of growth of brain white matter may result in uncoordinated nerve cell-synapse communications.

Other factors implicated in autism  including age of parents, seizure disorders, problems with immune system and endocrine/hormonal system, dysfunction of the mitochondria that are responsible for respiration at cellular level.

Disordered gut provides unifying framework underlying autism

Invoking the gut at the core of the disorder may provide a unifying framework for better understanding of autism and its multiple diverse manifestations. The range of presentations may vary based on the qualitative and quantitative differences of the digestive factors involved.

CLICK TO READ FULL ARTICLE

Other topics of interest:

Are micronutrients (vitamins and minerals) beneficial in autism?

Autism and constipation  controversy

Leaky gut syndrome

Is mangosteen good for health

Autism and leaky gut

Autism and gut bacteria  

Intestinal bacteria for health and disease

Gut bacteria genes and gut at interphase in autism 

L-carnitine treatment for autism

Vitamin D and autism

Migraine headache triggers  

Learn about celiac disease

Facebook LIKE Dr. Anil        Blog: Digestion, Health and Nutrition

Fact or Fiction: Increased GI Problems in Autism

espite the overwhelming observations by families and scientific there remains a small section  of scientific community that has questioned such a difference based on minority  of literature (Kuddo T et al, Black C et al).
In fact, an editorial in the journal Pediatrics (Gilger et al) stated with confidence that  “putting to rest the nagging suggestion that there exists a link between autism  and gastrointestinal disease”.  However, many experts have argued against putting too much stock in this.

                CLICK HERE TO READ FULL ARTICLE

Learn about 12-point autism treatment program   

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Study: micronutrients (vitamins and minerals) superior to drugs for autism

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By Anil Minocha MD, author: Guide to Alternative Medicine and the Digestive System

Micronutrient deficiencies have been reported in patients with autistic spectrum disorders/ autism. Limited Literature  suggests that an improvement in a variety of behavioral problems occurs upon  micronutrient (vitamins and minerals) supplementation. At the same time, systematic review published in the prestigious journal Pediatrics points out that most routinely used medications do not meet criteria for evidence based medicine.

Potential mechanism of beneficial effect of micronutrients in autism:

  • Antioxidant activity
  • Improved mitochondrial function
  • Micronutrients  function as cofactors and as such have potential to improve metabolic efficiency at the level of neurotransmitters.

Autism-micronutrient vs drugs study background:  Dr. Mehl-Madrona and colleagues from the University of Hawaii School of Medicine, Honolulu, Hawaii. University of Calgary Faculty of Medicine, Calgary, Alberta, Canada. University of Manitoba, Winnipeg, Manitoba, sought to compare effect of micronutrient supplementation versus standard medical treatment for treatment of autism.

Autism-micronutrient study: Micronutrient group comprised of 44 subjects (2-28 years) that desired treatment without pharmaceutical medications. They were compared to 44 autistic kids whose parents requested medical treatment.

Results of autism and micronutrient versus medications  study:

Both treatments were effective in improving Childhood Autism Rating Scale and the Childhood Psychiatric Rating Scale.

Whether the behavioral improvements occurred via effect on mood dysfunction or directly their impact on autistic disorder is open to speculation.

Conclusions of the micronutrient vs medication autism study:

  • Treatment with micronutrients offers better results with lower activity level, improved social interaction, reduced SIB, anger and irritability.
  • Superior results on micronutrient therapy alone are accompanied by fewer side-effects and lesser weight gain.
  • Medical treatment offered advantages of insurance coverage, fewer pills, and less frequent
    dosing.
  • Medical treatment is not superior to micronutrient management for any of the clinical parameters measured.

Caveat: Just like most  of the literature on autism, this study not meet the evidence level of a  randomized controlled trial and is more reflective of evidence relying on
practice based medicine.

Note: Micronutrient (vitamins and minerals) supplementation is part of the 12-point treatment program for autism.

 Topics below may be of interest or go to Home page

Are micronutrients (vitamins and minerals) beneficial in autism?

Autism and constipation  controversy

Leaky gut syndrome  

Is mangosteen good for health 

Autism and leaky gut

Autism and gut bacteria  

Intestinal bacteria for health and disease

Gut bacteria genes and gut at interphase in autism  

L-carnitine treatment for autism 

Vitamin D and autism

Migraine headache triggers  

Learn about celiac disease

Home page       Join Facebook group Autism: It’s Gut Stupid    Facebook Dr. Anil 

Blog: Digestion, Health and Nutrition