Enteric nervous system or second brain is more susceptible to mitochondrial dysfunction than brain
- Nervous system of the gut also known as enteric nervous system is susceptible to mitochondrial dysfunction even more than the brain and is consistent with increased prevalence of gastrointestinal symptoms in patients with primary inherited mitochondrial disorders.
- Not all regions of the gut and enteric nervous system or the “Second Brain” are equally affected during illness, a phenomenon seen in the central nervous system as well.
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