Do Tricyclic Antidepressants Help in Autism

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While the use of tricyclic antidepressents in autism is common, how sure are we that they are actually effective, or it merely a placebo effect with side-effects? How do side-effects square with the strength of evidence for their efficacy in autism?

TCA-Autism Spectrum Disorders Study

Dr. Hurwitz and colleagues from the Department of Community Pediatrics, Liverpool Hospital, in Liverpool BC, NSW, Australia, conducted a meta-analysis and systemetic review of efficacy of TCAs in patients with autism.

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